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1

Cyclization/Hydrosilylation of Functionalized 1,6-Diynes Catalyzed by Cationic Platinum Complexes Containing Bidentate Nitrogen Ligands

Wang, Xiang, Chakrapani, Harinath, Madine, James W., Keyerleber, Michele A., Widenhoefer, Ross A.

Journal:

Journal of Organic Chemistry

Année:

2002

Langue:

english

Fichier:

PDF, 153 KB

english, 2002

2

ChemInform Abstract: Synthesis of Carbobicyclic Compounds via Palladium-Catalyzed Cyclization/Hydrosilylation: Evidence for Reversible Silylpalladation.

Xiang Wang, Harinath Chakrapani, Carmine N. Stengone, Ross A. Widenhoefer

Journal:

Année:

2001

Fichier:

PDF, 34 KB

2001

3

Cyclization/Hydrosilylation of Functionalized 1,6-Diynes Catalyzed by Cationic Platinum Complexes Containing Bidentate Nitrogen Ligands.

Xiang Wang, Harinath Chakrapani, James W. Madine, Michele A. Keyerleber, Ross A. Widenhoefer

Journal:

Année:

2002

Langue:

english

Fichier:

PDF, 42 KB

english, 2002

4

Enantioselective Cyclization/Hydrosilylation of 1,6-Enynes Catalyzed by a Cationic Rhodium Bis(phosphine) Complex.

Harinath Chakrapani, Cong Liu, Ross A. Widenhoefer

Journal:

Année:

2003

Fichier:

PDF, 21 KB

2003

5

Synthesis, nitric oxide release, and anti-leukemic activity of glutathione-activated nitric oxide prodrugs: Structural analogues of PABA/NO, an anti-cancer lead compound

Harinath Chakrapani, Thomas C. Wilde, Michael L. Citro, Michael M. Goodblatt, Larry K. Keefer, Joseph E. Saavedra

Journal:

Bioorganic & Medicinal Chemistry

Année:

2008

Langue:

english

Fichier:

PDF, 240 KB

english, 2008

6

Synthesis, mechanistic studies, and anti-proliferative activity of glutathione/glutathione S-transferase-activated nitric oxide prodrugs

Harinath Chakrapani, Ravi C. Kalathur, Anna E. Maciag, Michael L. Citro, Xinhua Ji, Larry K. Keefer, Joseph E. Saavedra

Journal:

Bioorganic & Medicinal Chemistry

Année:

2008

Langue:

english

Fichier:

PDF, 430 KB

english, 2008

7

Synthesis and in vitro anti-leukemic activity of structural analogues of JS-K, an anti-cancer lead compound

Harinath Chakrapani, Michael M. Goodblatt, Vidya Udupi, Swati Malaviya, Paul J. Shami, Larry K. Keefer, Joseph E. Saavedra

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2008

Langue:

english

Fichier:

PDF, 215 KB

english, 2008

8

Synthesis and evaluation of piperazine and homopiperazine analogues of JS-K, an anti-cancer lead compound

Rahul S. Nandurdikar, Anna E. Maciag, Michael L. Citro, Paul J. Shami, Larry K. Keefer, Joseph E. Saavedra, Harinath Chakrapani

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2009

Langue:

english

Fichier:

PDF, 824 KB

english, 2009

9

Improved synthesis of V-PYRRO/NO, a liver-selective nitric oxide prodrug, and analogues

Sam Y. Hong, Joseph E. Saavedra, Larry K. Keefer, Harinath Chakrapani

Journal:

Tetrahedron Letters

Année:

2009

Langue:

english

Fichier:

PDF, 773 KB

english, 2009

10

An improved synthesis of V-PROLI/NO, a cytochrome P450-activated nitric oxide prodrug

Sam Y. Hong, Rahul S. Nandurdikar, Larry K. Keefer, Joseph E. Saavedra, Harinath Chakrapani

Journal:

Tetrahedron Letters

Année:

2009

Langue:

english

Fichier:

PDF, 541 KB

english, 2009

11

Design, Synthesis, and Evaluation of Thiol-Activated Sources of Sulfur Dioxide (SO 2 ) as Antimycobacterial Agents

Malwal, Satish R., Sriram, Dharmarajan, Yogeeswari, Perumal, Konkimalla, V. Badireenath, Chakrapani, Harinath

Journal:

Journal of Medicinal Chemistry

Année:

2012

Langue:

english

Fichier:

PDF, 481 KB

english, 2012

12

Synthesis, reactive oxygen species generation and copper-mediated nuclease activity profiles of 2-aryl-3-amino-1,4-naphthoquinones

Vinayak S. Khodade, Allimuthu T. Dharmaraja, Harinath Chakrapani

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2012

Langue:

english

Fichier:

PDF, 670 KB

english, 2012

13

Synthesis and antimycobacterial activity of prodrugs of sulfur dioxide (SO2)

Satish R. Malwal, Dharmarajan Sriram, Perumal Yogeeswari, Harinath Chakrapani

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2012

Langue:

english

Fichier:

PDF, 470 KB

english, 2012

14

P175. Allylic nitro compounds as sources of nitrite

Harinath Chakrapani, S. Bruce King

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 54 KB

english, 2006

15

Cross-Linking Protein Glutathionylation Mediated by O 2 -Arylated Bis-Diazeniumdiolate “Double JS-K”

Holland, Ryan J., Maciag, Anna E., Kumar, Varun, Shi, Lei, Saavedra, Joseph E., Prud'homme, Robert K., Chakrapani, Harinath, Keefer, Larry K.

Journal:

Chemical Research in Toxicology

Année:

2012

Langue:

english

Fichier:

PDF, 2.88 MB

english, 2012

16

Benzosultines as Sulfur Dioxide (SO 2 ) Donors

Malwal, Satish R., Gudem, Mahesh, Hazra, Anirban, Chakrapani, Harinath

Journal:

Organic Letters

Année:

2013

Langue:

english

Fichier:

PDF, 583 KB

english, 2013

17

Design, synthesis and evaluation of small molecule reactive oxygen species generators as selective Mycobacterium tuberculosis inhibitors

Dharmaraja, Allimuthu T., Alvala, Mallika, Sriram, Dharmarajan, Yogeeswari, Perumal, Chakrapani, Harinath

Journal:

Chemical Communications

Année:

2012

Langue:

english

Fichier:

PDF, 1.27 MB

english, 2012

18

INDQ/NO, a Bioreductively Activated Nitric Oxide Prodrug

Sharma, Kavita, Iyer, Aishwarya, Sengupta, Kundan, Chakrapani, Harinath

Journal:

Organic Letters

Année:

2013

Langue:

english

Fichier:

PDF, 772 KB

english, 2013

19

Structure Mechanism Insights and the Role of Nitric Oxide Donation Guide the Development of Oxadiazole-2-Oxides as Therapeutic Agents against Schistosomiasis

Rai, Ganesha, Sayed, Ahmed A., Lea, Wendy A., Luecke, Hans F., Chakrapani, Harinath, Prast-Nielsen, Stefanie, Jadhav, Ajit, Leister, William, Shen, Min, Inglese, James, Austin, Christopher P., Keefer,

Journal:

Journal of Medicinal Chemistry

Année:

2009

Langue:

english

Fichier:

PDF, 1.53 MB

english, 2009

20

C -Nitroso Donors of Nitric Oxide

Chakrapani, Harinath, Bartberger, Michael D., Toone, Eric J.

Journal:

Journal of Organic Chemistry

Année:

2009

Langue:

english

Fichier:

PDF, 134 KB

english, 2009

21

Arylboronate Ester Based Diazeniumdiolates (BORO/NO), a Class of Hydrogen Peroxide Inducible Nitric Oxide (NO) Donors

Dharmaraja, Allimuthu T., Ravikumar, Govindan, Chakrapani, Harinath

Journal:

Organic Letters

Année:

2014

Langue:

english

Fichier:

PDF, 432 KB

english, 2014

22

A Small Molecule for Controlled Generation of Reactive Oxygen Species (ROS)

Dharmaraja, Allimuthu T., Chakrapani, Harinath

Journal:

Organic Letters

Année:

2014

Langue:

english

Fichier:

PDF, 677 KB

english, 2014

23

Organic Sources of Sulfur Dioxide, a Reactive Sulfur Species

Chakrapani, Harinath, Malwal, Satish

Journal:

Free Radical Biology and Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 218 KB

english, 2012

24

Bioreductively-Activated Prodrugs of Nitric Oxide (NO)

Chakrapani, Harinath, Sharma, Kavita

Journal:

Free Radical Biology and Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 180 KB

english, 2012

25

EDINBURGH OBSTETRICAL SOCIETY.

Chakrapani, Harinath, Sharma, Kavita

Journal:

Année:

1913

Langue:

english

Fichier:

PDF, 420 KB

english, 1913

26

Design, Synthesis and Study of Reactive Oxygen Species Generators as Mycobacterium Tuberculosis Inhibitors

Chakrapani, Harinath, Dharmaraja, Allimuthu T

Journal:

Free Radical Biology and Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 231 KB

english, 2012

27

Nitroreductase-activated nitric oxide (NO) prodrugs

Sharma, Kavita, Sengupta, Kundan, Chakrapani, Harinath

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2013

Langue:

english

Fichier:

PDF, 692 KB

english, 2013

28

Bioreductively Activated Reactive Oxygen Species (ROS) Generators as MRSA Inhibitors

Khodade, Vinayak S., Sharath Chandra, Mallojjala, Banerjee, Ankita, Lahiri, Surobhi, Pulipeta, Mallikarjuna, Rangarajan, Radha, Chakrapani, Harinath

Journal:

ACS Medicinal Chemistry Letters

Année:

2014

Langue:

english

Fichier:

PDF, 385 KB

english, 2014

29

Nitric Oxide Prodrugs: Diazeniumdiolate Anions of Hindered Secondary Amines

Chakrapani, Harinath, Showalter, Brett M., Citro, Michael L., Keefer, Larry K., Saavedra, Joseph E.

Journal:

Organic Letters

Année:

2007

Langue:

english

Fichier:

PDF, 89 KB

english, 2007

30

Aryl Bis(diazeniumdiolates): Potent Inducers of S -Glutathionylation of Cellular Proteins and Their in Vitro Antiproliferative Activities

Andrei, Daniela, Maciag, Anna E., Chakrapani, Harinath, Citro, Michael L., Keefer, Larry K., Saavedra, Joseph E.

Journal:

Journal of Medicinal Chemistry

Année:

2008

Langue:

english

Fichier:

PDF, 459 KB

english, 2008

31

Glycosylated PROLI/NO Derivatives as Nitric Oxide Prodrugs

Nandurdikar, Rahul S., Maciag, Anna E., Hong, Sam Y., Chakrapani, Harinath, Citro, Michael L., Keefer, Larry K., Saavedra, Joseph E.

Journal:

Organic Letters

Année:

2010

Langue:

english

Fichier:

PDF, 444 KB

english, 2010

32

Synthesis of Carbobicyclic Compounds via Palladium-Catalyzed Cyclization/ Hydrosilylation: Evidence for Reversible Silylpalladation

Wang, Xiang, Chakrapani, Harinath, Stengone, Carmine N., Widenhoefer, Ross A.

Journal:

Journal of Organic Chemistry

Année:

2001

Langue:

english

Fichier:

PDF, 11 KB

english, 2001

33

Stabilization of the Nitric Oxide (NO) Prodrugs and Anticancer Leads, PABA/NO and Double JS-K, through Incorporation into PEG-Protected Nanoparticles

Kumar, Varun, Hong, Sam Y., Maciag, Anna E., Saavedra, Joseph E., Adamson, Douglas H., Prud’homme, Robert K., Keefer, Larry K., Chakrapani, Harinath

Journal:

Molecular Pharmaceutics

Année:

2010

Langue:

english

Fichier:

PDF, 564 KB

english, 2010

34

Site-directed delivery of nitric oxide to cancers

Sharma, Kavita, Chakrapani, Harinath

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 1011 KB

english, 2014

35

Activation of the c-Jun N-terminal Kinase/Activating Transcription Factor 3 (ATF3) Pathway Characterizes Effective Arylated Diazeniumdiolate-Based Nitric Oxide-Releasing Anticancer Prodrugs

Maciag, Anna E., Nandurdikar, Rahul S., Hong, Sam Y., Chakrapani, Harinath, Diwan, Bhalchandra, Morris, Nicole L., Shami, Paul J., Shiao, Yih-Horng, Anderson, Lucy M., Keefer, Larry K., Saavedra, Jose

Journal:

Journal of Medicinal Chemistry

Année:

2011

Langue:

english

Fichier:

PDF, 2.64 MB

english, 2011

36

A phenacrylate scaffold for tunable thiol activation and release

Sankar, Rathinam K., Kumbhare, Rohan S., Dharmaraja, Allimuthu T., Chakrapani, Harinath

Journal:

Chemical Communications

Année:

2014

Langue:

english

Fichier:

PDF, 1.16 MB

english, 2014

37

Substituent Effects on Reactive Oxygen Species (ROS) Generation by Hydroquinones

Dharmaraja, Allimuthu T., Jain, Charu, Chakrapani, Harinath

Journal:

Journal of Organic Chemistry

Année:

2014

Langue:

english

Fichier:

PDF, 397 KB

english, 2014

38

Allylic Nitro Compounds as Nitrite Donors

Chakrapani, Harinath, Gorczynski, Michael J., King, S. Bruce

Journal:

Journal of the American Chemical Society

Année:

2006

Langue:

english

Fichier:

PDF, 156 KB

english, 2006

39

The Nitric Oxide Prodrug V-PROLI/NO Inhibits Cellular Uptake of Proline

Hong, Sam Y., Borchert, Gregory L., Maciag, Anna E., Nandurdikar, Rahul S., Saavedra, Joseph E., Keefer, Larry K., Phang, James M., Chakrapani, Harinath

Journal:

ACS Medicinal Chemistry Letters

Année:

2010

Langue:

english

Fichier:

PDF, 1.18 MB

english, 2010

40

Enantioselective Cyclization/Hydrosilylation of 1,6-Enynes Catalyzed by a Cationic Rhodium Bis(phosphine) Complex

Chakrapani, Harinath, Liu, Cong, Widenhoefer, Ross A.

Journal:

Organic Letters

Année:

2003

Langue:

english

Fichier:

PDF, 59 KB

english, 2003

41

V-PROLI/NO, a Prodrug of the Nitric Oxide Donor, PROLI/NO

Chakrapani, Harinath, Showalter, Brett M., Kong, Li, Keefer, Larry K., Saavedra, Joseph E.

Journal:

Organic Letters

Année:

2007

Langue:

english

Fichier:

PDF, 80 KB

english, 2007

42

Cell-Permeable Esters of Diazeniumdiolate-Based Nitric Oxide Prodrugs

Chakrapani, Harinath, Maciag, Anna E., Citro, Michael L., Keefer, Larry K., Saavedra, Joseph E.

Journal:

Organic Letters

Année:

2008

Langue:

english

Fichier:

PDF, 293 KB

english, 2008

43

Synthesis of Carbobicyclic Compounds via Palladium−Catalyzed Cyclization/Hydrosilylation: Evidence for Reversible Silylpalladation

Wang, Xiang, Chakrapani, Harinath, Stengone, Carmine N., Widenhoefer, Ross A.

Journal:

Journal of Organic Chemistry

Année:

2001

Langue:

english

Fichier:

PDF, 80 KB

english, 2001

44

A highly selective sulfinate ester probe for thiol bioimaging

Malwal, Satish R., Labade, Ajay, Andhalkar, Abhijeet S., Sengupta, Kundan, Chakrapani, Harinath

Journal:

Chemical Communications

Année:

2014

Langue:

english

Fichier:

PDF, 1.79 MB

english, 2014

45

Benzosulfones as photochemically activated sulfur dioxide (SO 2 ) donors

Malwal, Satish R., Chakrapani, Harinath

Journal:

Organic & Biomolecular Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 797 KB

english, 2015

46

Thiol activated prodrugs of sulfur dioxide (SO2) as MRSA inhibitors

Pardeshi, Kundansingh A., Malwal, Satish R., Banerjee, Ankita, Lahiri, Surobhi, Rangarajan, Radha, Chakrapani, Harinath

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2015

Langue:

english

Fichier:

PDF, 542 KB

english, 2015

47

C-Nitroso Compounds: Synthesis, Physicochemical Properties and Biological Activities

Gooden, David, Chakrapani, Harinath, Toone, Eric

Journal:

Current Topics in Medicinal Chemistry

Année:

2005

Langue:

english

Fichier:

PDF, 138 KB

english, 2005

48

Mycobacterium tuberculosis has diminished capacity to counteract redox stress induced by elevated levels of endogenous superoxide

Tyagi, Priyanka, Dharmaraja, Allimuthu T., Bhaskar, Ashima, Chakrapani, Harinath, Singh, Amit

Journal:

Free Radical Biology and Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 2.37 MB

english, 2015

49

The Nitric Oxide Prodrug JS-K and Its Structural Analogues as Cancer Therapeutic Agents

Maciag, Anna, Saavedra, Joseph, Chakrapani, Harinath

Journal:

Anti-Cancer Agents in Medicinal Chemistry

Année:

2009

Langue:

english

Fichier:

PDF, 206 KB

english, 2009

50

A Small Molecule for Controlled Generation of Peroxynitrite

Khodade, Vinayak S., Kulkarni, Apoorva, Gupta, Ayantika Sen, Sengupta, Kundan, Chakrapani, Harinath

Journal:

Organic Letters

Année:

2016

Langue:

english

Fichier:

PDF, 1.11 MB

english, 2016